Scientists have generated structural images of a newly-described class of ion channels that help maintain the balance of pH inside brain cells. These molecular gates, called proton-activated chloride ...

Pharmacology has a cation bias. For too long, research has focused heavily on sodium and potassium channels, often treating anion transport as a secondary ...

For the first time, scientists have visualized a new class of molecular gates that maintain pH balance within brain cells, a critical function that keeps cells alive and helps prevent stroke and other ...

Every year, sepsis kills roughly 11 million people worldwide, more than lung cancer and heart attacks combined. Despite decades of research, no drug exists that directly strengthens the immune ...

A research team has discovered a previously unknown mechanism by which the immune system fights bacterial infections. The scientists found that a specific protein, the chloride channel PACC1, is ...