Scientists at the University of Bonn have clarified a surprising dual function of ceramide synthase. The enzyme not only catalyzes a central step of the production of vital lipids. It also has the ...

Ceramide transfer protein (CERT) transfers ceramide from the endoplasmic reticulum to the Golgi complex, a process critical in synthesis and maintenance of normal levels of sphingolipids in mammalian ...

Ceramides accumulate in the aged muscle – Researchers identify a new hallmark of ageing Researchers have uncovered sphingolipid accumulation as a new mechanism that affects ageing. Ceramides, the best ...

Acute kidney injury, or AKI, is a dangerous condition that affects many people in hospitals, especially those in intensive ...

A study carried out at the University of Helsinki and école Polytechnique Fédérale de Lausanne in Switzerland found that during aging, ceramides, a class of fat molecules called sphingolipids, start ...

Sphingolipids are bioactive molecules that have key roles in the regulation of cancer cell signalling to control tumour suppression or survival. Ceramide is a bioeffector molecule that mediates cell ...