However, antibody-mediated immunity involves a set of molecular components and processes that differ from cell-mediated immunity. In this article, we define humoral immunity and cell-mediated immunity ...

Adaptive immunity concerts two separate arms—humoral immunity driven by antibody-producing B cells, and cell-mediated immunity driven by “helper” T cells and “killer” T cells.

These results suggest that disrupting cancer-driven immune evasion mechanisms can restore T-cell-mediated immunity and enhance the effectiveness of immunotherapies, even in resistant tumors.

B-cell–mediated immunity predicts survival of patients with ER+ breast cancer. (A) The expression profiles of 70 B-cell–specific genes were visualized for TCGA patients with ER+ breast cancer, sorted ...

CD4⁺ and CD8⁺-mediated CTL recognition of these viral proteins can be detected with natural and vaccine-induced immunity. Responder cell frequencies for protein-specific T cell proliferation and CTL ...