EVOFLUx uses DNA methylation fluctuations as molecular barcodes to trace tumor evolution, offering insights into growth, treatment resistance, and prognosis. The method requires only bulk methylation ...

A review examines the prevailing theory of cancer evolution. The authors highlight both practical and theoretical limitations of the clonal model of cancer evolution and propose areas for improving ...

An international team led by the Clínic-IDIBAPS-UB along with the Institute of Cancer Research, London, has developed a new method based on DNA methylation to decipher the origin and evolution of ...

It’s not just size that matters. The speed of evolution can affect a species’ cancer prevalence too. Eric Isselee/Shutterstock A longstanding scientific belief about a link between cancer prevalence ...

The evolution of resistance to diseases, from infectious illnesses to cancers, poses a formidable challenge. Despite the expectation that resistance-conferring mutations would dwindle in the absence ...

Research led by Memorial Sloan Kettering Cancer Center (MSK) is shedding new light on how ovarian cancer evolves - insights that could help researchers develop more effective treatment strategies.

When cancer spreads from a primary tumor to new sites throughout the body, it undergoes changes that increase its genetic complexity. A new study from researchers at Weill Cornell Medicine and ...

The authors created detailed 3D renderings of tumors from more than 2,000 individuals, with breast, colon, pancreatic, kidney and uterine cancers, among others. From these detailed atlases, the ...

Antibody-drug conjugates represent a paradigm shift for patients with cancer and providers. Stacey Reeves' cancer journey only began a few years ago, but it has been filled with twists and turns. A 54 ...