The role of epigenetic mechanisms in cancer has gained interest in recent studies. The reversible nature of epigenetic changes on genomic DNA and histones holds promise for the development of ...

The scientists found that KLF5 had the greatest effect specifically promoting the growth and invasion of metastatic cells, ...

A new study shows that targeting key epigenetic proteins may permanently switch off cancer genes. Scientists at Monash University, working with Harvard University, report they have found a way to ...

Cancer mortality has just surpassed cardiovascular disease for the first time ever and one in two men, and one in three women, will be diagnosed with some form of the disease in the US, according to ...

Cellular findings show Telomir-Zn modulates intracellular metal balance linked to oxidative stress, mitochondrial dysfunction, DNA methylation instability, and genomic integrity-without relying on ...

Chromatin is one of the earliest identified targets for cancer therapeutics. Drug development aimed at altering chromatin can be traced to the differentiating agents of the 1970s and their link to DNA ...

Cancer has long been considered a disease driven by genetic mutations, but new research suggests that your risk may be ...

Methylation and cancer While these papers looked at the role of chromatin in the genetic expression of cancers, there are other laboratories looking at the role of methylation, another epigenetic ...

Combined epigenetic and immune checkpoint therapy altered the tumour microenvironment in platinum-resistant ovarian cancer.

In a lab-grown cell study focused on potential new treatment targets for halting the spread of most pancreatic cancers, Johns ...