(HealthDay News) — For patients with major depressive disorder, certain CYP2C19 polymorphisms contribute to citalopram (CIT) metabolism, according to research published in the December issue of the ...

We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. Non-carriers of the CYP2C19*2 loss-of-function genetic ...

Genetic polymorphisms have been described in the case of several CYP isoenzymes. The best explored example of this phenomenon is the CYP2C19 polymorphism. In this table the most frequent alleles are ...

(HealthDay News) — CYP2C19 polymorphism impacts response to proton pump inhibitor (PPI) treatment in gastroesophageal reflux disease (GERD), with lower efficacy rates for rapid metabolizer (RM) ...

tRNA-derived small RNA fragments (tRFs) as potential biomarkers for doxorubicin resistance in breast cancer. This is an ASCO Meeting Abstract from the 2019 ASCO Annual Meeting I. This abstract does ...

A total of 64 adults (>16 years of age) patients with epilepsy currently treated with PHT at standard daily dose (100–600 mg) were consecutively recruited from the Epilepsy Clinic at the INNN.

First-in-human trial focusing on the immunologic effects of the survivin-derived multiepitope vaccine EMD640744. This is an ASCO Meeting Abstract from the 2011 ASCO Annual Meeting I. This abstract ...

Patients with stable cardiovascular disease receiving clopidogrel have similar ischemic risk regardless of which variants of the drug-metabolizing CYP2C19 gene they carry, according to a substudy of ...

Proton pump inhibitor therapy is well tolerated at standard doses; even a fivefold increase in the AUC of PPIs appears to cause only negligible side effects. The clinical relevance of these ...