Communication between osteoblasts and endothelial cells (ECs) is essential for bone turnover, but the molecular mechanisms of such communication are not well defined. Here we identify Cxcl9 as an ...

In the July 12, 2021, issue of Nature Aging, researchers working at the Buck Institute for Research on Aging describe analysis from 1,001 immunomes of generally healthy patients correlating soluble ...

An inflammatory-aging clock called developed by Stanford University School of Medicine and the Buck Institute for Research on Aging can predict how strong your immune system will be in 10 years, when ...

Phase II pharmacodynamic trial of palbociclib in patients with KRAS mutant colorectal cancer. This is an ASCO Meeting Abstract from the 2015 Gastrointestinal Cancers Symposium. This abstract does not ...

In this new analysis, results showed that CCL3, CXCL8, CXCL9, and CXCL10 may be indicators of disease severity. Researchers are shedding light on serum indicators that may be associated with disease ...

A new study suggest that using CXCL9 and CXCL10-producing dendritic cells alongside immunotherapy can be a promising strategy to overcome treatment resistance and improve clinical outcomes for ...

Patients with acute tubulointerstitial nephritis (AIN), a difficult-to-diagnose allergic reaction in the kidneys, show substantial increases in the protein CXCL9 in their urine, suggesting an ...

Sobi® (STO: SOBI) today announced that topline results from the Phase 2a EMBRACE study evaluating Gamifant® (emapalumab) for interferon-gamma (IFNγ)-driven sepsis (IDS), showed proof-of-concept with ...

A new study has deciphered a complex molecular conversation between cancer and immune cells that is key to orchestrating the successful invasion of tumors by T cells that kill cancer cells. A Ludwig ...

AUGUST 3, 2023, NEW YORK – A Ludwig Cancer Research study has identified a pair of genes whose expression by a type of immune cell within tumors is predictive of outcomes for cancer patients and is ...

NETs promote macrophage expression of T-cell chemokines and subsequently facilitate cytotoxic CD8+ T cell infiltration and granzyme B production, which drives kidney fibrosis in obstructive ...