This is a rare feel-good moment in the antibiotic space. Shionogi manufactures and markets cefiderocol, a beta-lactam antibiotic that utilizes a clever siderophore strategy to enter and kill ...

Resistance to carbapenems among Enterobacterales is primarily achieved by production of carbapenemases, which are enzymes capable of hydrolyzing carbapenem antibiotics and most other beta-lactams and ...

MALVERN, Pa. & PARSIPPANY, N.J.--(BUSINESS WIRE)--Venatorx Pharmaceuticals (Venatorx) and Melinta Therapeutics (Melinta) announced today that the U.S. Food and Drug Administration (FDA) issued a ...

Bacteria can produce enzymes that make them resistant to antibiotics; one example is the TEM beta-lactamase enzyme, which enables bacteria to develop a resistance to beta-lactam antibiotics, such as ...

Crystal structure of the metallo-beta-lactamase protein 5-(pyridine-3-sulfonamido)-1,3-thiazole-4-carboxylic acid (ANT-431) (image by Simon Leiris). Researchers from the lab group of Michael Crowder, ...

Please provide your email address to receive an email when new articles are posted on . Some gram-negative bacilli, or GNB, are inherently resistant to certain antibiotics. Others acquire resistance ...

Some MRSA infections could be tackled using widely-available antibiotics, suggests new research from an international collaboration. Some MRSA infections could be tackled using widely-available ...

Basilea Pharmaceutica Ltd, Allschwil (SIX: BSLN), a commercial-stage biopharmaceutical company committed to meeting the needs of patients with severe bacterial and fungal infections, announced today ...

The Biomedical Advanced Research and Development Authority (BARDA) in the US will support Basilea’s development of a new type of oral antibiotic to treat complicated urinary tract infections (cUTIs).

Once seen as a lasting medical breakthrough, antibiotics are steadily losing their effectiveness. Around the world, ...