New research has identified a protein that could serve as both a biomarker and therapeutic target to weaken stem-like cancer ...

• BTK inhibitors work by targeting and blocking the BTK enzyme, which is crucial for the survival and growth of cancerous B-cells in mantle cell lymphoma (MCL). This cuts off the cancer cell’s support ...

Notch is one of the most frequently mutated genes in chronic lymphocytic leukemia (CLL), the most common leukemia in adults in the United States. It is also often mutated in other common B cell tumors ...

Mitochondrial defects are associated with the development of diseases such as type 2 diabetes (T2D). Studies in mice and in human tissues, by researchers at the University of Michigan, have now found ...

B cells are white blood cells that form a core part of the body's adaptive immune system, enabling it to recognize specific ...

Deep in the lungs, resident memory B cells stand guard against influenza reinfection—but whether they remain there may depend ...

A research team has made a major discovery on how the CUL5 gene affects CAR-T cell therapy, an advanced cancer therapy. The study reveals that reducing the activity of the CUL5 gene helps CAR-T cells ...