Lorundrostat, a drug that blocks aldosterone production from the adrenal glands, showed significant and lasting reductions in blood pressure in 1,083 patients with uncontrolled or resistant ...

Aldosterone synthase controls the synthesis of aldosterone and has been a pharmacologic target for the treatment of hypertension for several decades. Selective inhibition of aldosterone synthase is ...

Exercise cannot reduce a sodium-retaining hormone, aldosterone, which is known to potentially cause hypertension in African Americans. Many African Americans develop the salt-sensitive form of ...

Hypertension affects one in three adults globally and is the leading modifiable risk factor for cardiovascular disease. Aldosterone dysregulation, often driven by obesity and primary aldosteronism, ...