The Madrid derby takes center stage in the round of 16 of the Champions League, with Atletico Madrid in a commanding position to try to finally get the best of rival Real Madrid in the European competition.

Barcelona, Atlético Madrid and Real Madrid are this year's La Liga protagonists, but not only that, all three are still alive in the Copa del Rey semifinals and the Champions League round of 16. Unquestionably, three of the best teams in Europe this season.

Real Betis takes on Real Madrid at the Estadio Benito Villamarín in Seville on Saturday, March 1. Kickoff is set for 6:30 p.m. CET local time, making it a 12:30 a.m. ET and 9:30 a.m. PT start in the US, a 5:30 p.m. GMT start in the UK and a 4:30 a.m. AEDT kickoff in Australia on Sunday morning.